Undergraduate students Hongsen Qin, Emma Qian, Thomas Hoffmann, and Alexander Zlokapa (advised by Professors Aaron Ames, Erik Winfree, Jonathan Katz, Maria Spiropulu, and Yaser Abu-Mostafa) have won the Citadel Data Open International Data Science Competition. This winning team chose to investigate the optimal way to spend $1 billion to save lives from malaria and sanitation-related diseases, allocating funds for different prevention methods and optimizing budget breakdowns country by country. To quantify the socioeconomic impacts of their policy proposal, they modeled a variety of aspects from mosquito feeding cycles to climate change using techniques ranging from causal discovery methods to interpretable machine learning. The Caltech team was among 24 teams that were evaluated and questioned by a panel of experts including the former Chief Scientist of AI at Microsoft, a Princeton professor, and the chief of equities at Citadel. The Caltech team was chosen as the first place winner based on the depth, rigor, and comprehensiveness of their analysis.