Thesis Defense: Andrey Shur

Monday, December 13, 2021

3:00pm to 4:30pm

Online Event

Title:Serine Integrase-Based Event Recording in E. coliDescription:DNA is not only a wonder of the natural world but also a tool for information storage and retrieval. A genetic circuit has been developed that can enact specific and controlled genetic changes in response to changing small molecule concentrations. Known DNA sequences on plasmids can be repeatedly integrated into a synthetic array such that their identity and order encodes information about past small molecule concentrations that the cell has experienced. To accomplish this, catalytically inactive CRISPR-Cas9 (dCas9) is used to bind to and block attachment sites for the integrase Bxb1, and nanopore sequencing is used as the readout.Topic: Serine Integrase-based event recording in E. coli
Time: Dec 13, 2021 03:00 PM Pacific Time (US and Canada)Join Zoom Meeting

Meeting ID: 870 9244 6518

Passcode: andreyshur

For more information, please contact Monica Nolasco by phone at 6263954140 or by email at [email protected] or visit Zoom Link.

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